Volume 26; Issue suppl 2

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Annals of Oncology
Volume 26; Issue suppl 2

Annals of Oncology

Volume 26; Issue suppl 2

1

P6.15 * PEROXIREDOXIN 3 AS A MOLECULAR THERAPEUTIC TARGET IN BREAST CANCER

Chua, P. J., Chin, J., Chee, S., Thike, A. A., Yip, G., Tan, P. H., Bay, B. H.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

2

O6.1 * Classification of PARP inhibitors based on PARP trapping and catalytic inhibition, and rationale for combinations

Pommier, Y., Murai, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

3

P1.07 * Outcome of patients with relapsed/refractory lymphoma in a large cohort inside a phase 1 clinic department

Michot, J.- M., Benajiba, L., Baldini, C., Faivre, L., Danu, A., Hollebecque, A., Massard, C., Varga, A., Bahleda, R., Gazzah, A., Soria, J.- C., Ribrag, V.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

4

O3.1 * Targeting the estrogen receptor: old receptor, new drug(s)

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

5

P8.01 * PSMA ligands for diagnosis and therapy of prostate cancer

Haberkorn, U., Afshar-Oromieh, A., Giesel, F., Kopka, K., Eder, M., Babich, J., Kratochwil, C.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

6

P6.11 * Epigenetics and miRNA expression as mediators of A549 lung cancer cells resistance to DNA damaging anticancer drugs

El-Awady, R., Herzi, F., Al-Tunaiji, H., Saleh, E., Abd El-Wahab, A. E.- H., Homssi, A. A., Suhail, M., El-Sairafi, A., Al-Tel, T.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 26 KB

english, 2015

7

O4.3 * Chimeric Antigen Receptor (CAR) T Cell Therapy for B Cell Cancers

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

8

P6.14 * Identification of selective inhibitors of the spindle assembly checkpoint kinase TTK (Mps1) for treatment of triple negative breast cancer

Zaman, G., de Man, J., Uitdehaag, J., Maia, A., Boon, U., Sterrenburg, J.- G., Prinsen, M., Willemsen-Seegers, N., Jonkers, J., Kops, G., Medema, R., Buijsman, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 33 KB

english, 2015

9

O6.5 * MTH1 inhibitors in cancer treatment

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

10

P3.01 * Development and validation of a scalable next-generation sequencing system for assessing recurrent somatic alterations in solid tumors

Sherlock, J., Tomlins, S., Cani, A., Hovelson, D., Rhodes, K., Bien, G., Schageman, J., Gottimukkala, R., Bandla, S., Williams, P., Johnson, B., Sadis, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

11

O10.1 * Next generation ALK inhibitors and mechanisms of resistance to therapy

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

12

P3.02 * Clinical Survey of actionable proteins in multiple indications using multiplex mass spectrometry

Cecchi, F., Blackler, A., Jordan, H., Stocum, M., Darfler, M., Hembrough, T., Burrow, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

13

P6.04 * Application of Biosurfactants in Cancer Therapy

Akiyode, O., George, D., Boateng, J., Getti, G.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

14

P6.08 * Cationic porphyrin-phenazine conjugates as quadruplex DNA ligands and potential agents for anticancer therapy

Didan, Y., Dubey, L., Negrutska, V., Dubey, I.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

15

P4.09 * Role of Caspase-3 during TNF-alpha induced membrane molecule shedding from K-562 cells

Jurisic, V., Srdic-Rajic, T.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

16

P1.01 * A phase 3 study of the oral PARP inhibitor talazoparib (BMN 673) in BRCA mutation subjects with advanced breast cancer (EMBRACA)

Roche, H., Blum, J., Eiermann, W., Im, Y.- H., Martin, M., Mina, L., Rugo, H., Visco, F., Zhang, C., Lokker, N., Lounsbury, D., Litton, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 37 KB

english, 2015

17

O3.8 * Early Results: "ROCKET" a phase II Study of RRx-001, a novel triple epigenetic inhibitor, Resensitization to Irinotecan in Colorectal Cancer

Carter, C., Reid, T., Fisher, G., Cho-Phan, C., Kunz, P., Kaiser, H., Oronsky, B., Fanger, G., Caroen, S., Parker, C., Scicinski, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

18

O4.4 * Potent Antibody-Based Conjugates for Cancer Therapy: From Early Stage Research to a Clinically Approved Drug

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

19

O6.3 * ATR inhibitor AZD6738

Clack, G., Lau, A., Pierce, A., Smith, S., Stephens, C.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

20

O4.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

21

O6.4 * VX-970, selective inhibitor of ataxia telangiectasia and Rad3-related (ATR) protein

Asmal, M., Dean, E., Evans, J., Middleton, M., Plummer, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

22

O10.2 * HM61713, an EGFR-mutant selective inhibitor

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

23

P1.11 * Comparison of study designs, objectives and results of Phase I trials with cytotoxic versus non-cytotoxic anticancer agents

Hoffmans, R., Bosch, L., Klumper, E.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

24

P5.07 * Targeting AKT2 signalling events: improving therapeutic outcomes through cancer stemness modulation

Rafael, D., Gener, P., Pereira, L., Florindo, H., Schwartz, S., Videira, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 57 KB

english, 2015

25

P6.01 * Dramatic response to ASP-3026 in patient with highly aggressive pulmonary inflammatory myofibroblastic tumor harboring ALK rearrangement

Ono, A., Murakami, H., Wakuda, K., Taira, T., Kenmotsu, H., Naito, T., Ohde, Y., Endo, M., Nakajima, T., Takahashi, T.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 82 KB

english, 2015

26

LBA3 * Novel pyrazolopyrimidine derivatives inhibit angiogenesis and tumor growth in a mouse Lewis lung carcinoma model

Michailidou, M., Giannouli, V., Kostakis, I., Kotsikoris, V., Marakos, P., Pouli, N., Loutrari, H.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

27

O1.1 * Discovering selective anticancer drugs: Succeeding slowly is better than failing fast

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

28

O1.2 * Drugging the cancer genome to overcome drug resistance

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 22 KB

english, 2015

29

O9.1 * Perspectives from the RECIST committee on what constitutes a good tumor response metric

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 22 KB

english, 2015

30

P1.10 * A fully human anti-oxMIF antibody penetrates colorectal cancer metastases and accumulates in cancer tissue

Thiele, M., Schinagl, A., Douillard, P., Barak, H., Adib, D., Yazji, S., Scheiflinger, F., Kerschbaumer, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

31

LBA1 * A Novel Neutralizing Antibody Targeting PAPP-A Inhibits Tumor Growth and Ascites in Primary Patient Ovarian Tumorgrafts (Ovatars)

Becker, M., Haluska, P., Bale, L., Oxvig, C., Conover, C.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

32

O2.2 * PDL1 blockade in metastatic bladder cancer

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 21 KB

2015

33

O11.2 * AG-221 offers a survival advantage in a primary human IDH2 mutant AML xenograft model

Yen, K., Wang, F., Travins, J., Chen, Y., Yang, H., Straley, K., Choe, S., Dorsch, M., Agresta, S., Schenkein, D., Biller, S., Su, M.

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 62 KB

2015

34

P1.02 * MesomiR 1: A Phase I study of TargomiRs in patients with refractory malignant pleural mesothelioma (MPM) and lung cancer (NSCLC)

van Zandwijk, N., Pavlakis, N., Kao, S., Clarke, S., Lee, A., Brahmbhatt, H., Macdiarmid, J., Pattison, S., Leslie, F., Huynh, Y., Linton, A., Reid, G.

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 34 KB

2015

35

P7.02 * The clinical potential of ARGX-111, an afucosylated anti-MET antibody, in hematological malignancies and suppression of metastasis

Hanssens, V., De Jonge, N., Hultberg, A., Borg, C., Michieli, P., Dreier, T., de Haard, H., Thibault, A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

36

O3.6 * Combination of HSP90 inhibitor onalespib with crizotinib to treat or delay resistance in NSCLC: Preclinical and Clinical Investigations

Keer, H., Smyth, T., Courtin, A., Hearn, K., Lyons, J., Wallis, N., Oganesian, A., Azab, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

37

O8.4 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

38

O3.4 * A first-in-human study of intravenous BAL101553, a novel microtubule inhibitor, in patients with advanced solid tumors

Rhoda Molife, L., King, J., Smith, A., D'arcangelo, M., Brown, N., Diamantis, N., Lane, H., Schmitt Hoffmann, A. H., Engelhardt, M., Plummer, R., Kristeleit, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

39

O7.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

40

O7.3 * BET-bromodomain (BRD) inhibitor OTX015: Final results of the dose-finding part of a phase I study in hematologic malignancies

Herait, P., Dombret, H., Thieblemont, C., Facon, T., Stathis, A., Cunningham, D., Palumbo, A., Vey, N., Michallet, M., Recher, C., Rezai, K., Preudhomme, C.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

41

O7.6 * HSP90 inhibitors in the clinic: what have we learnt?

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

42

P1.14 * A Dose Escalation Single Arm Phase Ib Combination Study of BEZ235 with Everolimus in Patients with Advanced Solid Malignancies

Wise-Draper, T., Moorthy, G., Salkeni, M., Thomas, H., Mercer, C., Kozma, S., Thomas, G., Rixe, O., Desai, P., Morris, J., Olowokure, O.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

43

P1.05 * A ph 1 study of 2 different schedules of the PSMA-tubulysin small-molecule drug conjugate EC1169 in pts with rec Met Cast-Resist PC (MCRPC)

Tolcher, A., Ejadi, S., Sartor, A. O., Nguyen, B., Habbe, A., Vogelzang, N.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

44

P1.06 * Phase I study of the combination of alisertib (MLN8237) and gemcitabine in advanced solid tumors

Semrad, T., Kelly, K., Gandara, D., Riess, J., Li, T., Yu, A., Mack, P., Kim, E.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

45

P4.05 * The study of CD8+ T cell response to MHC class I-restricted universal tumoral peptide in accompany with viral peptide

Navashenaq, J. G., Shabgah, A. G., Hashemi, E. A., Seyedzadeh, M. H., Shokri, F., Razavi, S. A., Kardar, G. A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

46

P6.10 * Identifying ATMic non-small cell lung cancer cell lines: Implications for designing clinical trials

Bebb, G., Elegbede, A., Petersen, L., Williamson, C., Lees-Miller, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 54 KB

english, 2015

47

P8.08 * Roles of Nectin-4 in tumor progression

Ghidouche, A., Lopez, M., Olive, D.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

48

P8.09 * Case series of thyroid dysfunction induced by nivolumab (anti-PD-1; ONO-4538)

Tanaka, R., Fujisawa, Y., Maruyama, H., Nakamura, Y., Yoshino, K., Ohtsuka, M., Fujimoto, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

49

author index

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 39 KB

english, 2015

50

O10.4 * AZD9291 a novel EGFR-TKI that overcomes T790M-mediated resistance in NSCLC

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

51

P2.02 * Using modified Clostridium sporogenes as a delivery vehicle for anti-cancer therapeutics

Budd, P., Kubiak, A., Collery, M., Gustafsson, C., Minton, N., Kuehne, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 26 KB

english, 2015

52

P3.04 * Sprouty 2 protein, but not Sprouty 4, is an independent prognostic biomarker for human epithelial ovarian cancer

Masoumi-Moghaddam, S., Amini, A., Morris, D. L.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

53

P4.08 * Expression of Epidermal Growth Factor Receptor in Human Endometrial Hyperplasia and Carcinoma

Tavartkiladze, A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

54

P5.01 * A first in human, dose escalation trial of MSC2363318A - a dual p70S6K/Akt inhibitor, for patients with advanced malignancies

Tsimberidou, A. M., Verschraegen, C., Heestand, G., Kaleta, R., Scheuenpflug, J., Huck, B., Weise, A., Kurzrock, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 60 KB

english, 2015

55

O2.2 * PDL1 blockade in metastatic bladder cancer

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 21 KB

english, 2015

56

O11.2 * AG-221 offers a survival advantage in a primary human IDH2 mutant AML xenograft model

Yen, K., Wang, F., Travins, J., Chen, Y., Yang, H., Straley, K., Choe, S., Dorsch, M., Agresta, S., Schenkein, D., Biller, S., Su, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 62 KB

english, 2015

57

P1.02 * MesomiR 1: A Phase I study of TargomiRs in patients with refractory malignant pleural mesothelioma (MPM) and lung cancer (NSCLC)

van Zandwijk, N., Pavlakis, N., Kao, S., Clarke, S., Lee, A., Brahmbhatt, H., Macdiarmid, J., Pattison, S., Leslie, F., Huynh, Y., Linton, A., Reid, G.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

58

O9.4 * Effects of clinical uncertainties on fidelity of novel tumor response metrics and RECIST

Bottino, D., Kadakia, E., Chakravarty, A., Westin, E.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

59

P1.08 * A phase 1 study of 3 different schedules of the folic acid-tubulysin small-molecule drug conjugate EC1456 in pts with advanced solid tumors

Sachdev, J., Edelman, M., Harb, W., Matei, D., Nguyen, B., Burgess, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

60

P5.05 * Isolation of novel cell migration inhibitor migracins from Streptomyces and inhibition of cellular invasion in ovarian carcinoma cells

Ukaji, T., Umezawa, K.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 55 KB

english, 2015

61

P7.05 * Metal complexes of Meloxicam and Isoxicam decrease viability and proliferation of virus-transformed cancer cells

Zhivkova, T., Alexandrova, R., Dyakova, L., Georgieva, M., Miloshev, G., Culita, D.- C., Marinescu, G., Patron, L., Alexandrov, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

62

O2.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

63

O2.4 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

64

O2.5 * Novel immunostimulatory antibodies: What's next?

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 22 KB

english, 2015

65

O3.3 * Covalent CDK-7 inhibitors as new anti-cancer agents

Fritz, C., Schmidt, D., Choi, Y., Bradley, M., Brown, V., Sprott, K., Olson, E.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

66

P1.12 * A Phase I Dose Defining Study for MK-2206 Combined with Gefitinib in NSCLC Population Enriched with EGFR Mutation

Lin, C.- C., Yu, C.- J., Ho, C.- C., Chen, K.- Y., Shih, J.- Y., Lin, Z.- Z., Lin, Y.- L., Liao, W.- Y., Tsai, S.- H., Yan, L., Yang, J. C.- H.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

67

P5.02 * Development of Novel Anticancer Agents that Target Prohibitins and the Translation Initiation Factor eIF4A

Desaubry, L., Zhao, Q., Basmadjian, C., Thuaud, F., Ribeiro, N., Nebigil, C., Eggermont, A., Robert, C., Vagner, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 203 KB

english, 2015

68

P6.03 * In vivo assessment of growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine in peritoneal carcinomatosis models

Amini, A., Masoumi-Moghaddam, S., Morris, D. L.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

69

P6.07 * Real Time Photodynamic Therapy Analysis of ICG Loaded Modified Magnetic Nanoparticles on MCF-7 Cells

Sagir, T., Alt kardes, M., Burgucu, N., Karakas, N., Tabakoglu, O., Is k, S., Senel, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

70

P7.03 * Dianthin-EGF: a leading candidate in combination therapy with saponins in the field of colon carcinoma.

von Mallinckrodt, B., Thakur, M., Gilabert-Oriol, R., Fuchs, H., Melzig, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

71

O2.3 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

72

O8.2 * Putting adoptive T cell therapy on the path to regulatory approval

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 22 KB

english, 2015

73

P8.02 * Overexpression of PD-1 and PD-L1 in renal cell carcinoma is associated with poor prognosis in metastatic patients treated with sunitinib

Brunot, A., Rioux-Leclercq, N., Bensalah, K., Verhoest, G., Edeline, J., Bellaud, P., Viel, R., Jouan, F., Laguerre, B., Kammerer-Jacquet, S.- F.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

74

O7.2 * Phase 1 first-in-human study of the enhancer of zeste-homolog 2 (EZH2) histone methyl transferase inhibitor E7438

Ribrag, V., Soria, J.- C., Reyderman, L., Chen, R., Salazar, P., Kumar, N., Kuznetsov, G., Keilhack, H., Ottesen, L. H., Italiano, A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

75

O6.2 * Overview of clinical development programs, including potential combinations

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 21 KB

english, 2015

76

O11.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

77

P8.04 * Comparison of Human Nucleoside Transporter Interactions with BCR-ABL Kinase Inhibitors

Damaraju, V., Mowles, D., Cass, C., Sawyer, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

78

O4.5 * Cancer cells are addicted to inhibitors of apoptosis

Abastado, J.- P.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

79

P2.01 * ANG-1005 in Patients with Brain Metastases from Breast Cancer: Correlative Imaging with 18F-FLT-PET/CT

Bates, S., Lindenberg, M., Bryla, C., Patronas, N., Amiri-Kordestani, L., Fojo, T., Balasubramaniam, S., Choyke, P.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

80

P4.06 * Long-term molecular remission with an increase of WT1-specific CTLs after cessation of WT1 peptide vaccination in a patient with CML

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

81

LBA2 * Investigation of non-V600 BRAF mutations commonly found in NSCLC for their sensitivity to Dabrafenib or Trametinib

Noeparast, A., Verschelden, G., Umelo, I., de Brakeleer, S., Decoste, L., Teugels, E., de Greve, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

82

O3.5 * A Phase Ib dose escalation study of afatinib in combination with standard-dose cetuximab in patients with advanced solid tumours

Soria, J.- C., Boni, V., Gazzah, A., Holgado, E., Even, C., Ould-Kaci, M., Nazabadioko, S., Xue, W., Calvo, E.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

83

P2.06 * Curious controlled release of flutamide-related escape products under exposure to magnetic fields

Nakagawa, H., Kawase, H., Ohuchi, M., Ueno, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

84

P4.01 * In vivo synergism between chemotherapy and the 3C23K monoclonal antibody targeting the AMH-type II receptor in ovarian cancer PDX models

Nemati, F., Barret, J.- M., Massonnet, G., Bougherara, H., Nicolas, A., Martel, E., Donnadieu, E., Prost, J., Decaudin, D.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

85

P5.10 * Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells: significance of combination therapy

Amini, A., Masoumi-Moghaddam, S., Morris, D. L.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 52 KB

english, 2015

86

P8.06 * Liposomal drug delivery with anti-cancer flutamide-related radical pair system under exposure to pulsating electromagnetic fields

Nakagawa, H., Kawase, H., Ohuchi, M., Ueno, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

87

O9.5 * Novel multi-modal endpoints uncovered by radiogenomics integrating CT or MRI data

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 21 KB

english, 2015

88

O11.4 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

89

O3.2 * Phase I and dose ranging, phase II studies with IPH2201, a humanized monoclonal antibody targeting HLA-E receptor CD94/NKG2A

Seymour, L., Tinker, A., Hirte, H., Wagtmann, N., Dodion, P.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

90

P1.04 * Phase I dose escalation and expansion study to evaluate safety and efficacy of INC280 in patients with advanced MET-dependent solid tumors

Ma, B., Bang, Y.- J., Lim, W.- T., Nam, D.- H., Su, W.- C., Schellens, J. H. M., Azaro, A., Akimov, M., Zhang, Y., Kumar, A., Zhao, S., Schuler, M.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 33 KB

english, 2015

91

O5.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 15 KB

2015

92

O5.3 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 15 KB

2015

93

O5.4 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 15 KB

2015

94

O7.4 * Targeting BET bromo domain and other epigenetic modifiers for treatment of cancer

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 21 KB

english, 2015

95

O7.5 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

96

O8.1 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

97

O9.2 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

98

O9.3 *

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 16 KB

2015

99

O11.5 * Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

100

P5.03 * Control of cell fate by the mammalian target of rapamycin (mTOR) under stress depends on eIF2 serine 51 phosphorylation

Koromilas, A., Tenkerian, C., Krishnamoorthy, J., Kamindla, R., Wang, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 83 KB

english, 2015

101

P6.02 * Therapeutic Strategies of the Investigational New Drug, YQ23, for overcoming Chemoresistance in Hypoxic Solid Tumours

Man, C., Yau, T.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 24 KB

english, 2015

102

P7.01 * Characterization of 148 Ovarian Cancer tumografts (Avatars) using BROCA-HR deep sequencing

Lodhia, K., Becker, M., Hou, X., Kalli, K., Harrell, M., Wilcoxen, K., Swisher, E., Weroha, S., Halsuka, P.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

103

P7.04 * Influence of Deoxycholic acid and its metal complexes on viability and proliferation of human tumor cell lines

Dyakova, L., Zhivkova, T., Abudalleh, A., Culita, D.- C., Marinescu, G., Patron, L., Georgieva, M., Miloshev, G., Kalfin, R., Alexandrova, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

104

P8.05 * Selective targeting of CTNBB1-, KRAS- or MYC-driven cell growth by combinations of existing drugs

Zaman, G., Uitdehaag, J., De Roos, J., Van Doornmalen, A., Prinsen, M., Spijkers-Hagelstein, J., De Vetter, J., De Man, J., Buijsman, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

105

P8.07 * Novel mutational profiles in relapsed/refractory advanced cancer patients' pre- and post-targeted therapy

Mahadevan, D., Johnson, N., Pandey, M., Chandler, J., Cooke, L.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

106

O4.2 * Development of novel small molecule MerTK and Flt3 tyrosine kinase inhibitors for treatment of acute leukemia

Graham, D., DeRyckere, D., Minson, K., Smith, C., Hill, A., Huey, M., Lasater, E., Wang, X., Shah, N., Frye, S., Shelton Earp, H.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

107

O8.3 * Targeting tumor-associated macrophages in cancer patients

Ruttinger, D., Cassier, P., Cannarile, M., Ries, C., Gomez-Roca, C., D'Angelo, S., Weber, K., Campone, M., Le Tourneau, C., Delord, J.- P., Blay, J.- Y., Italiano, A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

108

O10.3 * Rociletinib: an oral, irreversible, highly selective small molecule inhibitor of mutant EGFR including T790M

Soria, J.- C., Sequist, L. V., Goldman, J., Wakelee, H. A., Neal, J., Camidge, R., Gadgeel, S., Papadimitrakopoulou, V., Dziadziuszko, R., Piotrowska, Z., Varga, A., Solomon, B. J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

109

O11.3 * Targeting isocitrate dehydrogenase (IDH)1 and IDH2 mutations Clinical results in advanced hematologic malignancies

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

110

P1.03 * Analysis of Biomarkers and PK Modeling of ABT-767 in Patients With BRCA1/BRCA2-Mutated Tumors or High Grade Serous Ovarian Cancer

de Jonge, M., van Herpen, C., Gietema, J., Timms, K., Dunbar, M., Hetman, R., Serpenti, C., Xiong, H., Zhu, M., Mittapalli, R., Ansell, P., Shepherd, S.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

111

P3.03 * AGATA molecular screening program: implementing precision medicine in patients with advanced breast cancer in Spain

Villagrasa, P., Ciruelos, E., Llombart-Cussac, A., Pena, L. d. l., Vazquez, J., Alonso, V., Vivancos, A.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

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